Esya in the Press
Esya has been featured by widely recognized national and international news outlets and prestigious science publications.
Transforming dementia care and diagnosis
Dhivya discusses the urgent need for integrating innovative diagnostics and therapies into the NHS in order to improve dementia care and diagnosis
Could This Blood Test Revolutionise How Dementia and Other Neurodegenerative Diseases Are Diagnosed?
Every 3.2 seconds someone in the world is diagnosed with dementia.
Yamuna Krishnan creates tiny machines from DNA for early and accurate disease diagnosis
Yamuna Krishnan is a professor of chemistry at the University of Chicago and the co-founder of Esya Labs.
Yamuna Krishnan’s Goal: Find Drugs for Neurodegenerative Diseases
Her company, Esya Labs, is developing DNA nanodevices that track drug responses, screen for new therapies and more
Esya Labs Provides Novel Research Assays to Accelerate Drug Discovery Efforts
Esya Labs, which is developing several ground-breaking novel research assays, today has announced that Novartis is among the first companies to use its technology.
Esya Labs and HeioThera Receive $250,000 Investment from the George Shultz Innovation Fund
The 2021 Spring Cohort of the George Shultz Innovation Fund has invested $250,000 in both Esya Labs and HeioThera – and this number will increase as they solidify additional funding.
From home-grown to international: New companies move into the Imperial Incubator
New residents at the Imperial Incubator have come from as far afield as Boston and as close to home as the South Kensington campus.
Yamuna Krishnan’s Goal: Find Drugs for Neurodegenerative Diseases
Her company, Esya Labs, is developing DNA nanodevices that track drug responses, screen for new therapies and more
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Discoveries Made With
Esya’s Technology
Esya’s technology has been featured in many influential publications in leading scientific journals
A biomarker panel reveals altered
lysosomal content in alzheimer’s disease
Using two-ion mapping technology, we quantitatively profiled lysosomal pH and Ca2+ in blood-derived monocytes from AD patients.
A DNA nanomachine that maps spatial and temporal pH changes inside living cells
DNA nanomachines are synthetic assemblies that switch between defined molecular conformations upon stimulation by external triggers.
A pH-correctable, DNA-based fluorescent reporter for organellar calcium
It is extremely challenging to quantitate lumenal Ca2+ in acidic Ca2+ stores of the cell because all Ca2+ indicators are pH sensitive, and Ca2+ transport is coupled to pH in acidic organelles.
High lumenal chloride in the lysosome is critical for lysosome function
Lysosomes are organelles responsible for the breakdown and recycling of cellular machinery.
Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell
DNA is a versatile scaffold for molecular sensing in living cells, and various cellular applications of DNA nanodevices have been demonstrated.
A DNA nanomachine chemically resolves lysosomes in live cells
Lysosomes are multifunctional, subcellular organelles with roles in plasma membrane repair, autophagy, pathogen degradation and nutrient sensing.
DNA nanodevices map enzymatic activity in organelles
Cellular reporters of enzyme activity are based on either fluorescent proteins or small molecules.
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Discoveries Made With
Esya’s Technology
Esya’s recent press
If you crave challenges, there’s no better place to be
Esya is a dynamic company operating at the intersection of biochemistry, technology and medicine. If you crave challenges and the chance to see your work impact the millions of lives touched by Alzheimer’s disease, there’s no better place to be.